Artificial TearsRx

Trade Names
Artificial tears:  Tears Naturale
Artificial tears, preservative free: Tears Naturale Free
Ocular ointments: Lacrilube
Ocular ointments, preservative free: Refresh PM, Lacriserts

Synonyms: Hydroxypropyl methylcellulose, hypromellose, ocular lubricants

Drug Class: Ophthalmic protectant

Preparations
Hypromellose 0.3%:  Tears Naturale,  Tears Naturale Free
Hydroxypropyl cellulose ocular system: Lacrisert 5-mg insert

Dose: One drop of a 0.3% tear solution applied topically to conjunctiva three to four times daily. In patients with keratoconjunctivitis sicca, drops should be applied regularly even if no symptoms are present. Some patients require more frequent application (every 2 hours). Hydroxypropyl cellulose 5- mg ophthalmic insert: use once or twice daily

Indications: Dry eyes

Mechanism of Action: Promotes corneal wetting by stabilizing and thickening the tear film

Contraindications: Hypersensitivity

Precautions: Use preservative-free preparations if preservative causes irritation.

Pregnancy Risk: C

Adverse Effects: Blurring of vision; eye irritation

Drug Interactions: None

Patient Instructions: Tears may be used as often as required. Regular use rather than waiting until symptoms are present is best. Do not instill with contact lens in place unless preparation is designed for use with contact lenses. Always wash hands before administration. Never touch tip of dropper to the eye surface.

Clinical Pharmacology: No systemic effects after ocular administration

Cost: $