Ketorolac
Last updated: October 17, 2014
Trade Names: Toradol
Drug Class: NSAID
Preparations
Tablet: 10 mg
Injection: 15 mg/mL (1 mL), 30 mg/mL (1 mL, 2 mL)
Dose
Tablet: 10 mg three to four times daily; maximum 40 mg/day; maximum 5 days administration
Injection: 30 mg then 15–30 mg every 6 hours as needed (maximum daily dose 120 mg)
Indications: Short-term management of acute pain
Comments: Only use for short-term control of pain. Lower doses in the elderly and if renal impairment.
Clinical Pharmacology: Well absorbed after oral administration; hepatic metabolism; renal excretion of 60% of drug unchanged. Half-life of 2–8 hours is increased in elderly persons.
Cost: $$$
See NSAIDs for Indications, Mechanism of Action, Contraindications, Precautions, Monitoring, Pregnancy Risk, Adverse Effects, Interactions, and Patient Instructions
BIBLIOGRAPHY
Gillis JC, Brogden RN. Ketorolac. A re-appraisal of its pharmacodynamic and pharmacokinetic properties and therapeutic use in pain management. Drugs 1997;53:139–188. PMID: 9010653